Creation of Parameter Sets for Exploration of Environmental Effects on the Course of Disease

Zigurds Markovics, Ieva Markovica

Abstract


The paper is devoted to the research problems, when influence of external environmental factors on healthy organism or the course of the disease is required. One of the first problems is to decide, what body parameters should be measured to evaluate most important impact factors. The easiest way is to measure everything that can be measured, or to use only in prac-tice applied measurements. However, the result is better if the set of parameters is purposefully selected, based on the efficiency parameters and overlapping all disease affected subsystems providing coverage of all pathogenic manifestations of the dis-ease. The authors suggest for this purpose to use the topological modeling of pathogenesis, formalized model processing, parame-ter evaluation, ranking and selection of parameters using the table overlay method.

Keywords:
Coverage, disease pathogenesis, environmental factors, expert evaluation, organism, topological model.

Full Text:

 PDF

References


R. A. Wallace, Biology: the World of Life, 6th ed., Harper Collins Publishers, 1992, p. 840.

P. O. Heller, Life. The Science of Biology, 3rd ed., p. 574.

L. S. Costanco, Physiology, 3rd ed., 2006, pp. 612.

I. Fox, Ph.D., Human Physiology, 2nd ed., p. 691.

M. Klavins, O. Nikodemus, V. Silins, V. Mellecis, M. Vircovs, K. Āboltiņa, “Environment science,” LU Academic Publisher, 2008, p. 599, ISBN 978-9984-825-09-7.

A. Peters, G. Hoek, K. Katsouyanni, “Understanding the link between environmental exposures and health: does the exposome promise too much?” J Epidemiol Community Health, Feb. 2012, vol. 66 (2), pp. 103–105. http://dx.doi.org/10.1136/jech-2011-200643

J. Vencloviene, R. Babarskiene, R.I. Kubilius, J. Stasionyte, “The effect of solar-geomagnetic activity during and after admission on survival in patients with acute coronary syndromes,” International Journal of Biometeorology, Aug 2014, vol. 58, issue 6, pp. 1295–1303. http://dx.doi.org/10.1007/s00484-013-0725-0

V. Rozhkov, N. Belisheva, A. Martynova, S. Soroko, “Psychophysiological and cardiohemodynamic effects of solar, geomagnetic, and meteorological factors in humans under the conditions of the arctic region,” Human Physiology, Jul 2014, vol. 40, issue 4, pp. 397–409. http://dx.doi.org/10.1134/S0362119714040124

“Ultravioletais starojums un tā ietekme uz cilvēka veselību,” Atlants, [Online]. Available: http://www.atlants.lv/referats/ultravioletais-starojumsun-ta-ietekme-uz-cilveka-/674868/

A. Ahlbom, M. Feichting, “Electromagnetic radiation,” Environmental Polution and Health British Medical Bulletin, 2003, vol. 68, pp. 157–165. http://dx.doi.org/10.1093/bmb/ldg030

“Health Criteria 137. Electromagnetic Fields,” Environmental Internationtional Programme on Chemical Safety, WHO, Geneva, 1993.

M. Papailioua, S. Dimitrova, E. S. Babayevc, H. Mavromichalakia, “Analysis of Changes of Cardiological Parameters at Middle Latitude Region in Relation to Geomagnetic Disturbances and Cosmic Ray Variations,” American Institute of Physics, 2009. http://dx.doi.org/10.1063/1.3322548

M. Piňosová, M. Andrejiová, E. Lumnitzer, “Analysis of clinical signs of noise exposure on human health in plants with high exposure to noise,” International J. of Engineering, T.XI, 2013, Fascicule, ISSN 1584-2665.

A. Blinovs “Atomelektrostaciju ietekme uz apkārtējo vidi,” [Online]. Available: http://www.atlants.lv/prezentacija/atomelektrostaciju-ietekmeuz-apkartejo-vidi/435190/

O. Coskun, “Magnetic resonance imaging and safety aspects,” Toxicology & Industrial Health, 05/01/2011, vol. 27, Issue 4, pp. 307–313.

A. K. Jha, A. M. Singh, B. Shetye, S. Shah, A. Agrawal, N. C. Purandare, P. Monteiro, V. Rangarajan, “Radiation safety audit of a high volume Nuclear Medicine Department,” Indian Journal of Nuclear Medicine, Oct–Dec 2014, vol. 29, Issue 4, pp. 227–234.

A. A. Kolodynski, V. V. Kolodynska, “Motor and Psychological Functions of Scool Children Living in the Area of the Skrunda Radio Location Station in Latvia,” The Science of the Total Enviroment, 1996, vol. 180, no. 1, pp. 87–93.

A. A. Kolodynski, V.V. Kolodynska, “Electromagnetic Fields: Legislation Research in Latvia,” Proc. Latvian Academy of Sciences, 2006, vol. 60, no. 1.

Y. Grigorjev, Mobile “Telecommunication: Radiobiological Issues and Risk Assesment,” Proc. Latvian Academy of Sciences, 2006, Sec.B, vol. 60, pp. 6–10.

I. Markovica, Z. Markovics, “Selection of parameters for differential diagnosis,” Cybernetics and Diagnostics, Riga, 1972, vol. 5, pp. 37–45. (in Russian).

J. Osis, J.A. Gelfandbein, Z. Markovics, N. Novozilova, “Diagnostics on Graph models,” Transport, Moscow, Transport, 1991, p. 245 (in Russian)

J. Osis, J. Grundspenkis, Z. Markovics, “Topological Modelling of Complex Heterogenus System. Theory and Aplications,” Riga Technical University, 2012, pp. 407. (in Latvian).

M. G. Hendall, J. D. Gobbons, Correlation methods, 5th ed., Arnat, London, UK, 1990, pp.114–121.

A. Voronin, The expert data processing method, Kiev, Naukova Dumka, 1974, pp. 97–103.




DOI: 10.7250/tcc.2014.005

Refbacks

  • There are currently no refbacks.